My CCRM IVF Journey

Our successful journey through IVF #2 at one of the world's top fertility clinics

I am a Believer (Day 6 Results)

Posted by auntiem10 on October 9, 2010

I am so shocked and thrilled to be able to write that we have SIX biospied blasts for genetic testing. Five embryos were biopsied today, and one was biopsied yesterday. And, even better, they are all great quality! All of the doubts I had going into today were baseless, and I have no doubt that the amazing lab at CCRM made a huge difference for us.

Here is a brief explanation of how CCRM grades embryos. A more technical explanation can be found here. First the staff assigns a number from 1-6 to indicate the expansion of the embryo. A rating of “1” means the embryo is hardly expanded at all, and a rating of “6” means the embryo is very expanded and even hatching. Second, they assign an alphabetic letter grading the cells that will later become the baby. Third, they assign an alphabetic letter grading the cells that will later become the placenta. For both cell masses, the grades may range from A-C. The best rating is “A,” but there are plenty of success stories even with embryos graded “C.”

Out of the 22 eggs that were mature and ICSI’d on Day 1 (boldfaced are the biopsied blasts):

Embryo #1: Fertilized abnormally
Embryo #2: Made it to early blast stage, but wasn’t good enough quality to grade or biopsy
Embryo #3: Graded 6AB; very expanded and already hatching
Embryo #4: Didn’t develop after fertilization
Embryo #5: Graded 6BA; looks very similar to Embryo #3
Embryo #6: Didn’t develop after fertilization
Embryo #7: Fertilized abnormally
Embryo #8: Did not pass the cleavage stage
Embryo #9: Did not pass the cleavage stage
Embryo #10: Degenerate and poor quality
Embryo #11: Did not pass the cleavage stage
Embryo #12: Did not pass the cleavage stage
Embryo #13: Graded 6BA; expanded and hatching
Embryo #14: Did not pass the cleavage stage
Embryo #15: (This embryo was biopsied yesterday) Graded 5AA; hatching
Embryo #16: Did not pass the cleavage stage
Embryo #17: Did not pass the cleavage stage
Embryo #18: Did not pass the cleavage stage
Embryo #19: Poor quality
Embryo #20: Graded 6AA
Embryo #21: Graded 5BA
Embryo #22: Did not pass the cleavage stage

We are thrilled!!! To experienced IVFers: one of my friends wrote that a grade of “6” means that the shell is too thin. Do you have any idea whether this is true? The lab told me they are great quality, so I’m not worrying to much, but Dr. Google isn’t telling me anything. I might request one more call from embryology to set my mind at ease.

Not all of these embryos are going to be chromosomally normal. We are hoping for half, which would be three. The embryologist said it might take a little longer than two weeks. And now we wait again. But for now, we are still in this game, and the lab exceeded our expectations by a mile!

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14 Responses to “I am a Believer (Day 6 Results)”

  1. Marcia said

    I’m so HAPPY for you!!!! Great news today. I will keep you in my prayers for sure.

  2. Jen said

    That is fabulous news! Yay! And I’ll root for more than half being normal. Enough to transfer soon and then more to transfer later!

  3. R said

    I’m so glad you have 6 to test. I wouldn’t worry about quality right now as you won’t know which ones are normal so the worry could be for nothing. Enjoy the little milestones as they come.

  4. mo said

    This is wonderful news!!! Fantastic!!! The 6 means that the blast has completely hatched. Two of the ones we just transferred were normal 6s. I asked the head embryologist about them ahead of time and he said that CCRM has a 98% thaw rate from vitrification. The 6s usually thaw just fine but they sometimes represent that 2% (ours both survived the thaw…). they told me they care much more about the letters than the numbers and you’ve got great letters! sending positive thoughts that many of these come back normal for transfer! Congratulations!

    Mo

  5. Lc1 said

    Yay!! So happy you got some beautiful blasts! Congrats!

  6. Deana said

    Yay, this is great news!! I’m so excited for you!!

  7. Susie said

    YAY!!! I am so happy for you. What a great way for me to start the day, with this wonderful news from you. And you only have a few more weeks to wait — that’s really great. They told us it would be up to 6 weeks but was more like 4, if I remember correctly. The waiting was tough for me but I hope you’ll be able to ride this high for much of it. Congratulations!! Yahoo!

  8. Pie said

    WOW! This is great news! Congrats, and bask in the glow of this good report for at least a week – it will make the wait more bearable! And just think, if you had done this a year ago, the wait was more like 4-6 weeks, so 2-ish weeks is nothing!! You can do it!

  9. Cassie said

    That is great news! And yes, your wait is so short compared to what we went through last year, so count your blessings! I’ve got a good feeling for you – you’ve got lots of good quality embies.

  10. LisainSK said

    That is SOO awesome!! In my research a 6 means it’s completely hatched and ready to go…so happy for you!

  11. Molly said

    Wow! Congratulations! I’m so glad to hear that things are going well so far.

  12. Running_girl said

    Awesome news! So happy for you!

  13. […] embryos, found out SIL’s baby is a girl, got the call that six great-quality embryos were biopsied for CCS testing, received CCS results SIX days later (five normals!), first Depot Lupron injection, received first […]

  14. […] Our Day 6 Biopsy Report […]

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